SLC12A2, solute carrier family 12 member 2, 6558

N. diseases: 128; N. variants: 7
Disease: Brain Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.030 Biomarker group BEFREE Due to its essential role in cell migration NKCC1 may serve as a specific therapeutic target to decrease cell invasion in patients with primary brain cancer. 28679472 2017
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.030 Biomarker group BEFREE Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. 22570591 2012
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.030 AlteredExpression group BEFREE Experiments were thus designed to investigate whether, in human epileptic peritumoral cortex, alterations in the balance of NKCC1 and KCC2 activity may decrease the hyperpolarizing effects of GABA, thereby contributing to epileptogenesis in human brain tumors. 21635237 2011