SLC15A1, solute carrier family 15 member 1, 6564

N. diseases: 31; N. variants: 4
Disease: Crohn Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.030 Biomarker disease BEFREE Inhibitory Potency of Marketed Drugs for Ulcerative Colitis and Crohn's Disease on PEPT1. 28867741 2017
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.030 AlteredExpression disease BEFREE PEPT1 expression was characterized in mouse models of Crohn's disease-like ileitis (Tnf) or colitis (Il-10, Il-10XTlr2) and endoscopic tissue samples from descending colon of patients with IBD (n = 11) and controls (n = 17). 24583477 2014
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.030 Biomarker disease BEFREE The intestinal transporter PepT1, encoded by the SLC15A1 gene, mediates intracellular uptake of bacterial products that can induce inflammation and NF-kappaB activation upon binding to NOD2, a protein often mutated in CD. 19462432 2009