Androgen receptor suppresses prostate cancer metastasis but promotes bladder cancer metastasis via differentially altering miRNA525-5p/SLPI-mediated vasculogenic mimicry formation.
In addition, the level of serum HOTAIR was positively associated with the levels of serum bone metabolic markers (CTx, OST, B-ALP and PINP) and may serve as a reasonable biomarker for PCa bone metastasis.
Bone morphogenetic proteins (BMPs) play a critical role in tumor progression and this study focuses on the role of BMP9- <i>A</i>ctivin receptor-<i>L</i>ike <i>K</i>inase 1 and 2 (ALK1 and ALK2) axis in prostate cancer.