SNCA, synuclein alpha, 6622

N. diseases: 449; N. variants: 66
Disease: Dementia in Parkinson's disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0349081
Disease: Dementia in Parkinson's disease
Dementia in Parkinson's disease 		0.040 Biomarker disease BEFREE Thus, therapies that target α-synuclein, tau, or amyloid β could potentially improve cognitive performance in PD. 23037886 2012
CUI: C0349081
Disease: Dementia in Parkinson's disease
Dementia in Parkinson's disease 		0.040 GeneticVariation disease BEFREE Alpha-synuclein promoter haplotypes and dementia in Parkinson's disease. 17918232 2008
CUI: C0349081
Disease: Dementia in Parkinson's disease
Dementia in Parkinson's disease 		0.040 Biomarker disease BEFREE Emerging evidence from pathology, as well as in-vivo studies using novel techniques within genetics, imaging, and cerebrospinal fluid research, indicates that alpha-synuclein aggregation and disturbances of other candidate proteins are associated with dementia in Parkinson's disease. 18989112 2008
CUI: C0349081
Disease: Dementia in Parkinson's disease
Dementia in Parkinson's disease 		0.040 Biomarker disease BEFREE Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease. 17683088 2007