SOD1, superoxide dismutase 1, 6647

N. diseases: 689; N. variants: 68
Disease: Influenza A ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 Biomarker disease BEFREE However, 4-phenylbutyrate (4-PBA), an inhibitor of ER stress signaling, weakened the effect of IAV infection on SOD1 loss in a dose-dependent manner. 30905731 2019
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 AlteredExpression disease BEFREE Therefore, we concluded that early stage IAV infection induces autophagic degradation of antioxidant enzyme SOD1, thereby contributing to increased ROS generation and viral infectivity in alveolar epithelial cells. 29548827 2018
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 Biomarker disease BEFREE Emodin also activated the Nrf2 pathway, decreased ROS levels, increased GSH levelss and GSH/GSSG ratio, and upregulated the activities of SOD, GR, CAT and GSH-Px after IAV infection. 29057806 2017