BNIP3L, BCL2 interacting protein 3 like, 665

N. diseases: 63; N. variants: 10
Disease: Amyotrophic Lateral Sclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		0.010 Biomarker disease BEFREE The upregulation of a specific subset of BH3-only proteins, including Bid, DP5/Hrk, and BNip3L, in reactive astrocytes suggests that these proteins may execute a novel <i>non-apoptotic</i> function within astrocytes to promote ALS disease progression, thus providing a new potential target for therapeutic intervention. 29440992 2018