SOX11, SRY-box transcription factor 11, 6664

N. diseases: 246; N. variants: 8
Disease: Hematopoietic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0376544
Disease: Hematopoietic Neoplasms
Hematopoietic Neoplasms 		0.030 Biomarker group BEFREE Promoter methylation of tumor suppressor gene SOX11 has been reported to contribute to the diagnosis and prognosis of various cancerous diseases, including gastric cancer, hematopoietic malignancies and nasopharyngeal carcinoma. 26925788 2016
CUI: C0376544
Disease: Hematopoietic Neoplasms
Hematopoietic Neoplasms 		0.030 AlteredExpression group BEFREE In recent years, aberrant SOX11 expression has been observed in various solid and hematopoietic malignancies, including GC. 25801783 2015
CUI: C0376544
Disease: Hematopoietic Neoplasms
Hematopoietic Neoplasms 		0.030 Biomarker group BEFREE Thus, these data demonstrate a tumor suppressor function for SOX11 in hematopoietic malignancies and revealed a potential epigenetic regulation of this developmentally involved gene. 20624318 2010