Disease: Adult Medulloblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.040 AlteredExpression disease BEFREE In this study, we show that SPARC expression induces cisplatin resistance in medulloblastoma cells. 25014664 2014
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.040 AlteredExpression disease BEFREE In this study, we demonstrate that expression of SPARC inhibits medulloblastoma cell proliferation. 22206672 2012
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.040 AlteredExpression disease BEFREE SPARC overexpression in Daoy medulloblastoma cells inhibited migration and invasion in vitro. 21798346 2011
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.040 Biomarker disease BEFREE Taken together, our results suggest that SPARC induces expression of neuronal markers in medulloblastoma cells through its inhibitory effect on IL-6-regulated suppression of Notch pathway-mediated STAT3 signaling, thus giving further support to the potential use of SPARC as a therapeutic candidate for medulloblastoma treatment. 21613407 2011