Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 AlteredExpression disease BEFREE High expression of nuclear YAP1 in tumor stroma was significantly correlated with SPARC expression and fibrosis degree in human PDAC tissues. 31352078 2019
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 Biomarker disease BEFREE Global SPARC ablation reduces the collagen-rich microenvironment in murine PDAC. 31597597 2019
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 Biomarker disease BEFREE <b>Background:</b> The predictive roles of secreted protein acidic and rich in cysteine (SPARC) in pancreatic ductal adenocarcinoma (PDAC) patients after curative resection have not been clarified. 30719160 2019
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 Biomarker disease BEFREE A peritumoral staining was confirmed for α-SMA, tenascin C, SPARC and NT-3 in the PDAC TMA cohort (n = 223). 29778400 2018
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 Biomarker disease BEFREE Stromal SPARC and cytoplasmic SPARC were examined immunohistochemically in 211 PDAC patients treated with adjuvant GS or G alone after resection. 29295776 2018
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 AlteredExpression disease BEFREE Conditioned medium of PDAC cells reduced endogenous SPARC expression of PSCs. 19920824 2010
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 Biomarker disease BEFREE This evidence supports a protumorigenic role of osteopontin and points to an antitumorigenic role of osteonectin in PDAC. 20495387 2010
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.080 AlteredExpression disease BEFREE There was a 31-fold increase in osteonectin mRNA levels in PDAC and a 16-fold increase in chronic pancreatitis as compared with the normal pancreas (P < 0.01). 16041213 2005