SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Disease: Adrenoleukodystrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy 		0.020 AlteredExpression disease BEFREE OPN expression positively correlated with disease severity in patients with progressive stages of ALD. 25278703 2014
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy 		0.020 AlteredExpression disease BEFREE In conclusion, the current study suggests that OPN is induced by EtOH and its metabolite ACA and opposite relationship likely exist between PPAR-alpha and OPN expression within the liver during ALD. 18703563 2008