SPRR2A, small proline rich protein 2A, 6700

N. diseases: 67; N. variants: 0
Disease: Memory impairment ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.010 AlteredExpression phenotype BEFREE Tanshinone IIA (Tan IIA, 80 mg/kg) administration notably protected mice from Aβ<sub>25-35</sub> -induced spatial memory impairment and neurotoxicity, increased pERK/ERK and the expression of RACK1, and reduced the elevated levels of BECLIN1 and LC3-II/I in the hippocampus. 27882565 2017