SRD5A2, steroid 5 alpha-reductase 2, 6716

N. diseases: 106; N. variants: 55
Disease: Androgenetic Alopecia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162311
Disease: Androgenetic Alopecia
Androgenetic Alopecia 		0.420 GeneticVariation disease GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
CUI: C0162311
Disease: Androgenetic Alopecia
Androgenetic Alopecia 		0.420 AlteredExpression disease BEFREE Collectively, the enhanced expression of type II 5α-reductase, AR and Hic-5/ARA55 can upregulate sensitivity to androgen of dermal papilla cells in AGA. 21167691 2011
CUI: C0162311
Disease: Androgenetic Alopecia
Androgenetic Alopecia 		0.420 Biomarker disease CTD_human 5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia. 17136762 2007
CUI: C0162311
Disease: Androgenetic Alopecia
Androgenetic Alopecia 		0.420 GeneticVariation disease BEFREE The purpose of our study is to investigate the genetic polymorphisms of steroid 5alpha-reductase type 1 and 2 (SRD5A1 and SRD5A2) genes in Korean population, and to study the association of these polymorphisms with the development, clinical types (female or male pattern) and therapeutic response of androgenetic alopecia. 12670724 2003