BRCA1, BRCA1 DNA repair associated, 672

N. diseases: 747; N. variants: 2600
Disease: Medullary carcinoma of breast ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0860580
Disease: Medullary carcinoma of breast
Medullary carcinoma of breast 		0.070 GeneticVariation disease BEFREE Methylation of the promoter of the BRCA1 gene detectable in peripheral blood DNA may be a marker of increased susceptibility to triple-negative or medullary breast cancer. 25376744 2014
CUI: C0860580
Disease: Medullary carcinoma of breast
Medullary carcinoma of breast 		0.070 GeneticVariation disease BEFREE The SIRs of medullary breast cancer agreed with the BRCA1 mutation prevalences detected by the German Consortium for Hereditary Breast and Ovarian Cancer. 15668291 2005
CUI: C0860580
Disease: Medullary carcinoma of breast
Medullary carcinoma of breast 		0.070 GeneticVariation disease BEFREE A total of 3 mutations in BRCA1 were identified among 14 (21.4%) women with a medullary breast carcinoma. 16168118 2005
CUI: C0860580
Disease: Medullary carcinoma of breast
Medullary carcinoma of breast 		0.070 GeneticVariation disease BEFREE MBC patients have an excess of BRCA1 germ-line mutation and reliable identification of MBC could help to identify patients at risk of carrying germline BRCA1 mutations or in whom chemotherapy could be avoided. 16167361 2005
CUI: C0860580
Disease: Medullary carcinoma of breast
Medullary carcinoma of breast 		0.070 GeneticVariation disease BEFREE Previous reports have suggested an association between medullary breast cancer and BRCA1 mutation carriers. 15039599 2004
CUI: C0860580
Disease: Medullary carcinoma of breast
Medullary carcinoma of breast 		0.070 Biomarker disease BEFREE Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors. 14614327 2004
CUI: C0860580
Disease: Medullary carcinoma of breast
Medullary carcinoma of breast 		0.070 GeneticVariation disease BEFREE Mutations at BRCA1: the medullary breast carcinoma revisited. 9563465 1998