DisGeNET - a database of gene-disease associations

SREBF1, sterol regulatory element binding transcription factor 1, 6720

N. diseases: 159; N. variants: 12

Disease: Malignant neoplasm of pancreas ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0346647
Disease:	Malignant neoplasm of pancreas

Malignant neoplasm of pancreas

0.030

Biomarker

disease

BEFREE

However, the relationship between high glucose microenvironment, SREBP1 and pancreatic cancer remains to be explored.

31296258

2019

CUI:	C0346647
Disease:	Malignant neoplasm of pancreas

Malignant neoplasm of pancreas

0.030

Biomarker

disease

BEFREE

However, the impact of SREBP1 activation in the progression of pancreatic cancer has not been explored.

28483521

2017

CUI:	C0346647
Disease:	Malignant neoplasm of pancreas

Malignant neoplasm of pancreas

0.030

AlteredExpression

disease

BEFREE

High expression of SREBP1 predicted poor prognosis in patients with pancreatic cancer.

25589463

2015