SST, somatostatin, 6750

N. diseases: 535; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Performance of <sup>68</sup>Ga-DOTA-Conjugated Somatostatin Receptor-Targeting Peptide PET in Detection of Pheochromocytoma and Paraganglioma: A Systematic Review and Metaanalysis. 30030341 2019
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 AlteredExpression disease BEFREE Ga-DOTANOC PET/CT is well documented in evaluation of well-differentiated neuroendocrine tumors and in other lesions with somatostatin receptor expression such as pheochromocytoma, paraganglioma, neuroblastoma, meningioma, and mesenchymal tumors causing oncogenic osteomalacia. 30829863 2019
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Because SSTR profiles vary in PHEOs and PGLs, individual analysis is required for each tumor. 30529752 2019
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE <sup>68</sup>Ga-somatostatin receptor analogs and <sup>18</sup>F-FDG PET/CT in the localization of metastatic pheochromocytomas and paragangliomas with germline mutations: a meta-analysis. 29566550 2018
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Somatostatin receptor-targeting endoradiotherapy offers potential for treating metastatic pheochromocytomas and paragangliomas, an approach likely to benefit from combination radiosensitization therapy. 30288966 2018
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Herein we report the case of a female patient with a right suprarenal mass, which was suspected to be an atypical pheochromocytoma based on a history of the classic triad and positive somatostatin receptor scintigraphy, but histopathology suggested a final diagnosis of right suprarenal splenosis. 28860051 2017
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Pheochromocytomas/paragangliomas overexpress somatostatin receptors, and recent studies have already shown excellent results in the localization of sympathetic succinate dehydrogenase complex, subunit B, mutation-related metastatic pheochromocytomas/paragangliomas using (68)Ga-DOTATATE PET/CT. 26564322 2016
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Usefulness of Somatostatin Receptor Scintigraphy (Tc-[HYNIC, Tyr3]-Octreotide) and 123I-Metaiodobenzylguanidine Scintigraphy in Patients with SDHx Gene-Related Pheochromocytomas and Paragangliomas Detected by Computed Tomography. 25791839 2015
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 AlteredExpression disease BEFREE High somatostatin receptor expression on the cell membrane of succinate dehydrogenase mutation-related pheochromocytoma and paraganglioma provides a potential target for imaging and therapy. 26152741 2015
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE We investigated the effects of the new somatostatin analog (pasireotide) SOM230 versus octreotide (OCT) in primary PHEO cell cultures (Pheo-c). 18502819 2008
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE These findings suggest that SRIH analogs with enhanced SSTR2 affinity might be useful in the medical therapy of PC, even when an OctreoScan is negative. 12920656 2003
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Six somatostatin (SS) receptor (SSR) positive tumors (two gastrinomas, three carcinoids, one pheochromocytoma) and one SSR negative tumor (renal cell carcinoma), selected by positive and negative SSR autoradiography, respectively, were studied by both immunohistochemistry and Western blot analysis. 10022452 1999
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
0.100 Biomarker disease BEFREE Molecular and pharmacological characterization of somatostatin receptor subtypes in adrenal, extraadrenal, and malignant pheochromocytomas. 7775631 1995