SSTR5, somatostatin receptor 5, 6755

N. diseases: 75; N. variants: 7
Disease: insulinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021670
Disease: insulinoma
insulinoma 		0.030 AlteredExpression disease BEFREE SSTR5 knockdown by short hairpin RNA led to increased PDX-1 expression that was accompanied by enhanced insulin secretion stimulated by high glucose in β-TC6 cells and alternated expressions of cell cycle proteins that favor cell proliferation in mouse insulinoma MIN6 cells. 22669743 2012
CUI: C0021670
Disease: insulinoma
insulinoma 		0.030 Biomarker disease BEFREE The observed positive correlation between SSTR5 expression and tumour size suggests that the use of SST analogues more specific to SSTR5 in the treatment of insulinomas deserves attention. 16601280 2006
CUI: C0021670
Disease: insulinoma
insulinoma 		0.030 AlteredExpression disease LHGDN Somatostatin receptors 2 and 5 are the major somatostatin receptors in insulinomas: an in vivo and in vitro study. 14602773 2003