SSTR5, somatostatin receptor 5, 6755

N. diseases: 75; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker disease PSYGENET These genes include GRM7, previously associated to major depression disorder and bipolar disorder, SLC6A13, in anxiety disorders, and S100B, SSTR5 and COMT in schizophrenia. 20398908 2010
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker disease BEFREE Our results may indicate that the SSTR5 gene is involved in the etiology of BPAD or may exist in linkage disequilibrium with a susceptibility gene close to SSTR5. 12192619 2002
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker disease PSYGENET Our results may indicate that the SSTR5 gene is involved in the etiology of BPAD or may exist in linkage disequilibrium with a susceptibility gene close to SSTR5. 12192619 2002
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker disease PSYGENET These genes include GRM7, previously associated to major depression disorder and bipolar disorder, SLC6A13, in anxiety disorders, and S100B, SSTR5 and COMT in schizophrenia. 20398908 2010
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.300 Biomarker disease PSYGENET These genes include GRM7, previously associated to major depression disorder and bipolar disorder, SLC6A13, in anxiety disorders, and S100B, SSTR5 and COMT in schizophrenia. 20398908 2010
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.300 Biomarker disease CTD_human At 4 weeks after SE, SRIF1-family (SSTR 2A, SSTR2B, and SSTR5) immunoreactivity was increased only in neuropil. 18951627 2009
CUI: C0270823
Disease: Petit mal status
Petit mal status
0.300 Biomarker disease CTD_human The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. 18951627 2009
CUI: C0311335
Disease: Grand Mal Status Epilepticus
Grand Mal Status Epilepticus
0.300 Biomarker disease CTD_human The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. 18951627 2009
CUI: C0393734
Disease: Complex Partial Status Epilepticus
Complex Partial Status Epilepticus
0.300 Biomarker disease CTD_human The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. 18951627 2009
CUI: C0751522
Disease: Status Epilepticus, Subclinical
Status Epilepticus, Subclinical
0.300 Biomarker disease CTD_human The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. 18951627 2009
CUI: C0751523
Disease: Non-Convulsive Status Epilepticus
Non-Convulsive Status Epilepticus
0.300 Biomarker disease CTD_human The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. 18951627 2009
CUI: C0751524
Disease: Simple Partial Status Epilepticus
Simple Partial Status Epilepticus
0.300 Biomarker phenotype CTD_human The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. 18951627 2009
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.200 Biomarker disease RGD Pituitary and hypothalamic somatostatin receptor subtype messenger ribonucleic acid expression in the food-deprived and diabetic rat. 7956902 1994
CUI: C0001430
Disease: Adenoma
Adenoma
0.100 AlteredExpression group BEFREE The intensity of SSTR5 expression and the granulation pattern of adenomas were of limited value for the prediction of Pasireotide-LAR effectiveness. 31518993 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression group BEFREE SSTR1 to SSTR5 expression in PC tumors. 30657933 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression group BEFREE We found somatostatin receptor type 5 (SST5) expressed in 17 different ACTH-secreting tumors and SST2 detectable in 15 out of the 17 tissues. 30611770 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE IHC evaluation of tumor samples from two patients (a responder and a non-responder) revealed positive immunostaining for PRL and SSTR5 but not for other pituitary hormones or for SSTR2. 29948930 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE Monoclonal antibodies to somatostatin receptors 2A (SSTR2A, UMB-1) and 5 (SSTR5, UMB-4) were reported to be highly reliable for immunohistochemical detection of these receptors in neuroendocrine neoplasms. 29180250 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression group BEFREE Neither sinonasal carcinomas nor sinonasal small round blue cell neoplasms expressed SSTR2A or SSTR5. 29807052 2018
CUI: C0001430
Disease: Adenoma
Adenoma
0.100 AlteredExpression group BEFREE RESULTS IHC of SSTR subtypes in the different cohorts showed SSTR2 staining intensity scores higher than SSTR5 in TSHoma, acromegaly and prolactinoma, whereas the expression of SSTR5 was stronger than SSTR2 in corticotropinoma and NFPA. 28434012 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE Similarly, SSTR5 was increased in pancreatic and well-differentiated tumors. 28454229 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE In conclusion, the protein expression of SSTR2, but not of SSTR5, is a valuable indicator in predicting biochemical and tumor size response to short-term SSA treatment in acromegalic patients. 28396686 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE CXCR4 and SSTR1 were present in 60% and 67% of the CCC samples, respectively, followed by SSTR2 and SSTR5, which were detected in 30% and 11% of the tumors, respectively. 29282035 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression group BEFREE All the eight tumor specimens expressed high SSTR2 protein levels; 5/8 expressed high SSTR5, but 3/8 that expressed low SSTR5 presented a significantly higher TSH suppression rate (P = 0.036). 28397723 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression group BEFREE One well-differentiated and two poorly differentiated neuroendocrine neoplasms expressed somatostatin receptor 5. 28059098 2017