Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Impact of age at onset on the phenomenology of depression in treatment-seeking adults in the STAR*D trial. 31740109 2020
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Focusing on insomnia symptoms to better understand depression: A STAR*D report. 31499373 2020
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Supervised machine-learning methods trained using SNPs and total baseline depression scores predicted remission and response at 8 weeks with area under the receiver operating curve (AUC) > 0.7 (P < 0.04) in PGRN-AMPS patients, with comparable prediction accuracies > 69% (P ≤ 0.07) in STAR*D and ISPC. 31012492 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE The STAR*D trial model estimates accurately predicted remission (area under the curve = 0.80) and no meaningful benefit (area under the curve = 0.82) in the Combining Medications to Enhance Depression Outcomes trial and was used to develop an interactive calculator. 30958879 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Latent transition analysis was applied to data from 387 men who completed baseline and Week 12 study visits in Level 1 of STAR*D. Items from the self-report version of the Quick Inventory of Depressive Symptomatology were used as indicators of latent depression subtypes. 26438468 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Patient-reported data on patients with depression from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial (n = 4039) were used to identify clusters of symptoms in a depressive symptom checklist. 28241180 2017
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE SLC6A4 polymorphisms and age of onset in late-life depression on treatment outcomes with citalopram: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) report. 23973251 2014
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Linear regressions tested the effect of polygenic risk scores for bipolar disorder on proportional reduction in depression severity in two large samples of individuals with MDD, treated with antidepressants, NEWMEDS (n=1,791) and STAR*D (n=1,107). 24339138 2014
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE A meta-analysis was performed on data from three genome-wide pharmacogenetic studies (the Genome-Based Therapeutic Drugs for Depression [GENDEP] project, the Munich Antidepressant Response Signature [MARS] project, and the Sequenced Treatment Alternatives to Relieve Depression [STAR*D] study), which included 2,256 individuals of Northern European descent with major depressive disorder, and antidepressant treatment outcomes were prospectively collected. 23377640 2013
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Targeted analysis of HTR2A in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study reveals associations between functional variants and depression severity or citalopram response. 23158458 2013
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE Caucasian non-Hispanic participants in the STAR*D study of treatment for depression for whom DNA was available (N = 1213) were genotyped at two single-nucleotide polymorphisms (SNPs) (rs10848635 and rs1006737) in the CACNA1C gene. 19388002 2010
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE The influence of genetic variations in SLC6A4 (serotonin transporter gene) on citalopram treatment of depression using the Sequenced Treatment to Relieve Depression (STAR*D) sample was assessed. 18618621 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Income and attrition in the treatment of depression: a STAR*D report. 19582825 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Family history of depression and therapeutic outcome: findings from STAR*D. 19192454 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE A total of 339 inpatients with a depressive episode (MARS sample), a further 361 inpatients with depression (German replication sample), and 832 outpatients with major depression (STAR*D sample). 19736353 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. 18191112 2008