Disease: Congenital neutropenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0340970
Disease: Congenital neutropenia
Congenital neutropenia 		0.030 AlteredExpression disease BEFREE Furthermore, G-CSFR d715 suppressed unfolded protein response and apoptosis induced by an SCN-derived NE mutant, which was associated with sustained activation of AKT and STAT5, and augmented expression of BCL-XL. 28073911 2017
CUI: C0340970
Disease: Congenital neutropenia
Congenital neutropenia 		0.030 Biomarker disease BEFREE These data add to our knowledge of SCN and further highlight the importance of STAT5 in mediating proliferative responses to G-CSF. 18513286 2008
CUI: C0340970
Disease: Congenital neutropenia
Congenital neutropenia 		0.030 AlteredExpression disease BEFREE These data provide insight into SCN unresponsive to standard G-CSF treatment and to the potential corrective action of combined treatment with G-CSF and corticosteroids through synergistic activation of STAT5. 11146160 2000