STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Disease: Keratosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022593
Disease: Keratosis
Keratosis 		0.010 GeneticVariation disease BEFREE In addition, within the BRAF inhibitor-associated group, the lesions designated as KAs and BRAF inhibitor-associated verrucous keratoses had a similar mutational profile (mutations in PIK3CA, APC, and HRAS), which was distinct to that seen in squamous cell carcinomas (FGFR3, CDKN2A, and STK11). 26319365 2015