STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Disease: Multiple Sclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.020 GeneticVariation disease BEFREE We previously reported that a single nucleotide polymorphism in the gene encoding LKB1 is a risk factor for multiple sclerosis (MS). 31664743 2020
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.020 GeneticVariation disease BEFREE In vitro studies showed that peripheral blood mononuclear cells from members of the family were more sensitive to the mitochondrial inhibitor metformin than cells from MS patients with the major STK11 allele. 25694554 2015