STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600113
Disease: Stromal tumor of ovary
Stromal tumor of ovary
0.020 Biomarker disease BEFREE Is loss of heterozygosity at 9q22.3 (PTCH gene) and 19p13.3 (STK11 gene) involved in the pathogenesis of ovarian stromal tumors? 16084949 2005
CUI: C0600113
Disease: Stromal tumor of ovary
Stromal tumor of ovary
0.020 Biomarker disease BEFREE Our results indicate that LOH at 19p13.3 in sporadic SCSTs targets a gene different from STK11, and may play a role in the pathogenesis of sporadic SCSTs, especially in tumors containing sex cord derivatives. 15343512 2004