STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Disease: Familial Retinoblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751483
Disease: Familial Retinoblastoma
Familial Retinoblastoma 		0.010 GeneticVariation disease BEFREE Germline loss of function mutations in tumor suppressor genes RB1 and LKB1/STK11 are associated with the autosomal dominant cancer predisposing syndromes familial retinoblastoma and Peutz-Jeghers syndrome (PJS), respectively. 23463749 2013