STX1A, syntaxin 1A, 6804

N. diseases: 74; N. variants: 9
Disease: Abnormal behavior ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior 		0.030 Biomarker phenotype BEFREE A part of patients with autism spectrum disorder has haploidy of HPC-1/syntaxin1A gene that possibly causes behavioral disturbance as in experimentally gene ablated mice. 28235601 2017
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior 		0.030 Biomarker phenotype BEFREE Genes encoding these proteins (SNAP25, VAMP1, VAMP2, STX1A, SYT1 and SYT2) have been studied in relation to psychiatric disorders susceptibility. 26856328 2016
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior 		0.030 Biomarker phenotype BEFREE HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems. 20576034 2010