|
Bile duct carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Also, the ESR2 rs4986938 (38 bp 3' of STP) GG genotype was associated with a higher risk of bile duct cancer (OR = 3.3, 95% CI 1.3-8.7) compared with the AA genotype, although this estimate was based on a small number of subjects.
|
20172949 |
2010 |
|
Cardiovascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
The role of sulphotransferases (SULT1A1/2) in cardiovascular disease requires further exploration.
|
18259693 |
2009 |
|
Cervical intraepithelial neoplasia grade 1
|
0.010 |
Biomarker
|
disease |
BEFREE |
Besides, three (50%) out of six detected CIN 1 lesions were PST+.
|
20129068 |
2009 |
|
Cervical intraepithelial neoplasia grade 2
|
0.010 |
Biomarker
|
disease |
BEFREE |
88.2% (60/68) of the histologically confirmed CIN 3 lesions and six out of nine (66.6%) CIN 2 lesions were positive PST+.
|
20129068 |
2009 |
|
Acute Chest Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The GALNT4 (N-acetyl galactosaminyl transferase 4) 506I allele was significantly underrepresented in ACS (OR = 0.66, CI = 0.52-0.84; P = 0.001; P = 0.01 after correction for multiple testing), while the SULT1A1 (Sulphotransferase 1A1) 213H allele was associated with risk of ACS (OR = 1.37, CI = 1.08-1.74; P = 0.01; P = 0.1 after correction for multiple testing).
|
18259693 |
2009 |
|
Carcinoma in situ of uterine cervix
|
0.010 |
Biomarker
|
disease |
BEFREE |
88.2% (60/68) of the histologically confirmed CIN 3 lesions and six out of nine (66.6%) CIN 2 lesions were positive PST+.
|
20129068 |
2009 |
|
Cervical Squamous Cell Carcinoma In Situ
|
0.010 |
Biomarker
|
disease |
BEFREE |
88.2% (60/68) of the histologically confirmed CIN 3 lesions and six out of nine (66.6%) CIN 2 lesions were positive PST+.
|
20129068 |
2009 |
|
Cervical Squamous Intraepithelial Neoplasia 1
|
0.010 |
Biomarker
|
disease |
BEFREE |
Besides, three (50%) out of six detected CIN 1 lesions were PST+.
|
20129068 |
2009 |
|
Cervix Intraepithelial Neoplasia Grade 3 AJCC v7
|
0.010 |
Biomarker
|
disease |
BEFREE |
88.2% (60/68) of the histologically confirmed CIN 3 lesions and six out of nine (66.6%) CIN 2 lesions were positive PST+.
|
20129068 |
2009 |
|
Brain Neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Our findings have suggested that there was a significant association between brain tumor and SULT1A1*2 allele (A allele that is also known as His allele) and this allele is an important risk factor in the development of meningiomal brain tumors.
|
17605044 |
2008 |
|
Brain Neoplasms
|
0.010 |
GeneticVariation
|
group |
LHGDN |
Our findings have suggested that there was a significant association between brain tumor and SULT1A1*2 allele (A allele that is also known as His allele) and this allele is an important risk factor in the development of meningiomal brain tumors.
|
17605044 |
2008 |
|
Glioma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Results of the statistical analyses of each group of patients in comparison with the control individuals showed a significant difference only between SULT1A1 polymorphism and non-glial brain tumors (OR = 2.615; 95% CI = 1.192-5.739; P = 0.014) but glial tumors (OR = 1.535; 95% CI = 0.688-3.425; P = 0.293).
|
17605044 |
2008 |
|
Neoplasms, Multiple Primary
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
To study the association of SULT1A1*2 polymorphism with tobacco-related cancers (TRCs), a case-control study comprising 132 patients with multiple primary neoplasm (MPN) involving TRC and 198 cancer-free controls was carried out.
|
18854828 |
2008 |
|
Pancreatic carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
To test the hypothesis that genetic variations in carcinogen metabolism modify the risk of pancreatic cancer (PC), we investigated the effect of single-nucleotide polymorphisms (SNPs) of the CYP1A2, NAT1, NAT2 and SULT1A1 gene on modification of the risk of PC in a hospital-based study of 755 patients with pancreatic adenocarcinoma and 636 healthy frequency-matched controls.
|
18499698 |
2008 |
|
Malignant neoplasm of pancreas
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
To test the hypothesis that genetic variations in carcinogen metabolism modify the risk of pancreatic cancer (PC), we investigated the effect of single-nucleotide polymorphisms (SNPs) of the CYP1A2, NAT1, NAT2 and SULT1A1 gene on modification of the risk of PC in a hospital-based study of 755 patients with pancreatic adenocarcinoma and 636 healthy frequency-matched controls.
|
18499698 |
2008 |
|
Brain Tumor, Primary
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The present study has investigated the association between SULT1A1 polymorphism and primary brain tumor incidence.
|
17605044 |
2008 |
|
Genitourinary Cancer
|
0.010 |
Biomarker
|
disease |
BEFREE |
The SULT1A1*2 revealed contrasting risk association for UADT cancers (OR=1.62, 95% CI: 1.12, 2.34) and genitourinary cancers (OR=0.73, 95% CI: 0.58, 0.92).
|
18854828 |
2008 |
|
ovarian neoplasm
|
0.010 |
GeneticVariation
|
disease |
LHGDN |
Comparative analysis of SNP in estrogen-metabolizing enzymes for ovarian, endometrial, and breast cancers in Novosibirsk, Russia.
|
18497059 |
2008 |
|
Chronic myeloproliferative disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
SULT1A1*2 showed significant risk association with UADT-MPN (odds ratio (OR)=5.50, 95% confidence interval (CI): 1.09, 27.7).
|
18854828 |
2008 |
|
Prostate cancer, familial
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The present study was conducted to confirm the association of a G638A polymorphism, Arg213His, in SULT1A1 with familial prostate cancer risk in a Japanese population.
|
18368507 |
2008 |
|
Hyperplastic Polyp
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We found evidence for interaction between NAT acetylator status and SULT1A1 genotype in risk of hyperplastic polyps: individuals with SULT1A1 638AA genotype and NAT1 and NAT2 intermediate/fast phenotypes had 3.5-fold increased risk (95% CI 1.2-10.3) compared with individuals with SULT1A1 638GG genotype and NAT1 and NAT2 slow phenotypes.
|
16926176 |
2007 |
|
Female Genital Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
A DNA bank of gynecologic oncology patients, patients with benign gynecologic diseases and healthy women was created, and the following single nucleotide polymorphisms (SNPs) were examined: CYP1A1 M1 polymorphism, that is, T264 --> C transition in the 3'-noncoding region; CYP1A2*1F polymorphism, that is, C734 --> A transversion in CYP1A2 gene; C --> T transition (Arg264Cys) in exon 7 of CYP19; SULT1A1*2 polymorphism, that is, G638 --> A transition (Arg213His) in SULT1A1 gene.
|
16402077 |
2006 |
|
Mucocutaneous Lymph Node Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
VEGF plasma levels were significantly higher in patients with the early phase of KD than in the healthy controls, and there was a trend toward higher VEGF plasma levels in KD patients with the -2594 CC and 236 bp 3' of STP CC genotypes.
|
16645995 |
2006 |
|
Malignant Head and Neck Neoplasm
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These preliminary findings show for the first time that the SULT1A1 His (213) allele is a possible risk factor for head and neck cancer development.
|
16575574 |
2006 |
|
MRSA - Methicillin resistant Staphylococcus aureus infection
|
0.010 |
Biomarker
|
disease |
BEFREE |
Recently, some of these isolates were shown to have the same genetic backgrounds as contemporary epidemic MRSA isolates, and Danish methicillin-susceptible S. aureus (MSSA) isolates from the 1960s with a PST antibiotype were proposed to have been the recipients of the mecA gene in those lineages.
|
17005800 |
2006 |