SYP, synaptophysin, 6855

N. diseases: 243; N. variants: 3
Disease: Forgetful ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0542476
Disease: Forgetful
Forgetful 		0.020 Biomarker phenotype BEFREE Here, we tested the hypothesis that reactive astrocytes-mediated loss of synaptophysin (SYP) and CREB-regulated transcription coactivator 1 (CRTC1) contribute to dysfunction in glia gap junction communication and memory impairment after ischemic stroke. 31270712 2019
CUI: C0542476
Disease: Forgetful
Forgetful 		0.020 AlteredExpression phenotype BEFREE Results from this study showed that DSP administration effectively ameliorated Aβ-induced learning and memory impairment in rats, markedly inhibited Aβ-induced hippocampal ROS production, effectively prevented Aβ-induced hippocampal neuronal damage and significantly restored hippocampal synaptophysin expression level. 28119081 2017