SYT1, synaptotagmin 1, 6857

N. diseases: 460; N. variants: 15
Disease: Induced hypothermia (finding) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1301797
Disease: Induced hypothermia (finding)
Induced hypothermia (finding) 		0.010 PosttranslationalModification phenotype BEFREE Here we show that the transcription factor NF-κB p65 is phosphorylated at Ser276 and activates RBM3 gene transcription via binding to a particular element within the promoter region in response to induced hypothermia, elevating the protein expression, and suppressing apoptosis. 29388696 2018