TACR1, tachykinin receptor 1, 6869

N. diseases: 217; N. variants: 10
Disease: Rheumatoid Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.030 AlteredExpression disease BEFREE Importantly, NK-1R expression was found to be significantly increased in RA-FLSs compared to normal FLSs. 31010320 2019
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.030 AlteredExpression disease LHGDN Regulation of neurokinin-1 receptor messenger RNA expression in synovial fibroblasts of patients with rheumatoid arthritis. 16154193 2005
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.030 AlteredExpression disease BEFREE These results suggest that bFGF, TGF-beta1, and TNF-alpha in synovial tissue and fluid play a role in the regulation of long NK1R expression in synovial fibroblasts of RA patients. 16154193 2005
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.030 AlteredExpression disease BEFREE These results provide histochemical evidence that rheumatoid synoviocytes strongly express NK1 gene, and the positive relation of the signal intensity of NK1 mRNA with CRP and radiographic severity suggests that the facilitation of NK1 gene expression in rheumatoid synovium relate the disease progression of RA. 9572640 1998