TACR1, tachykinin receptor 1, 6869

N. diseases: 217; N. variants: 10
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 GeneticVariation disease BEFREE Out of six SNPs tested in the TACR1 gene, one (rs11688000) showed a nominally significant association with a decreased risk of symptomatic OA in the discovery cohort. 28493529 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 AlteredExpression disease LHGDN Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the NK-1 receptor. 18289674 2008
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 AlteredExpression disease BEFREE Substance P receptor (NK1) gene expression in synovial tissue in rheumatoid arthritis and osteoarthritis. 9572640 1998