TACR1, tachykinin receptor 1, 6869

N. diseases: 217; N. variants: 10
Disease: Childhood Astrocytoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4086152
Disease: Childhood Astrocytoma
Childhood Astrocytoma 		0.030 AlteredExpression disease BEFREE In the present study, we investigated the anti-inflammatory effects of ketamine on the SP-induced activation of a human astrocytoma cell line, U373MG, which expresses high levels of NK-1R. 28204809 2017
CUI: C4086152
Disease: Childhood Astrocytoma
Childhood Astrocytoma 		0.030 AlteredExpression disease BEFREE As a model system, we used the human astrocytoma cell line U373 MG as well as primary rat astroglial cells, which both are known to express functional neurokinin-1 receptors (NK-1-R) and to secret various cytokines upon stimulation with SP. 16806114 2006
CUI: C4086152
Disease: Childhood Astrocytoma
Childhood Astrocytoma 		0.030 AlteredExpression disease BEFREE The binding of fluorescently labeled substance P and neurokinin A was tested on the human astrocytoma cell line UC11 that expresses endogenous NK(1) receptor. 10415087 1999