Disease: Renal Cell Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.040 Biomarker disease BEFREE TAP abnormalities do not appear to be attributable to structural alterations because no mutations in TAP1 were detected in TAP1-deficient RCC lesions. 12738726 2003
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.040 AlteredExpression disease BEFREE Here, we investigate the differential responsiveness to IFN-gamma of RCC cell lines, Caki-1 and Caki-2, which have been reported to have abnormally low expressions of TAP1 and LMP2. 11059775 2000
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.040 Biomarker disease BEFREE These studies suggest that abnormalities of MHC-class-I surface expression due to dysfunctional peptide transporters contribute to the immune escape phenotype of RCC cells and that the immune tolerance of RCC could be altered by TAP1-gene transfer. 10077163 1999
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.040 PosttranslationalModification disease BEFREE IFN-gamma-mediated coordinated transcriptional regulation of the human TAP-1 and LMP-2 genes in human renal cell carcinoma. 9815722 1997