Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.030 GeneticVariation group BEFREE Overall, the results suggest that TAP2 rs241447 polymorphism contributes to decreased cancer susceptibility. 31074096 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.030 AlteredExpression group BEFREE Further in-silico results indicated the expression of TAP2 in cancer tissue is higher than that in normal tissue (cervical cancer, TPM = 70.2 vs. 24.0 respectively, P <  0.01; acute myeloid leukemia, TPM = 52.5 vs. 8.8 respectively, P <  0.01), and influence the survival time of acute myeloid leukemia patients (Log-rank P <  0.05). 30082158 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.030 Biomarker group BEFREE The cell cycle delay of Psf1/Psf2-depleted HDF was associated with several hallmarks of pre-malignancy including gammaH2AX, Thr 68-phosphorylated Chk2, and increased numbers of aberrant fragmented nuclei. 19377277 2009