MIR582, microRNA 582, 693167

N. diseases: 47; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Hsa_circ_0009361 acted as a tumor suppressive sponge of miR-582, which could up-regulate the expression of APC2, inhibit the Wnt/β-catenin signaling, and suppress the growth and metastasis of CRC. 31109967 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE miR-582-5p is a potential prognostic marker in human non-small cell lung cancer and functions as a tumor suppressor by targeting MAP3K2. 30536321 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Moreover, restoration of AKT3 could impair tumor suppression role of miR-582-5p on gastric cancer growth. 29228422 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE However, the use of a specific miR‑582 inhibitor counteracted these effects. miR‑582 may also play an oncogenic role by promoting tumor growth in vivo. 28713947 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Our data suggest that miR-582-5p may function as a tumor suppressor in the development of CRC by targeting Rab27a, indicating a novel therapeutic strategy for patients with CRC. 26384136 2015