|
Carcinoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Elevated levels of the GCF mRNA were also noted in KATO III and AGS (gastric carcinomas), FEM-X (melanoma), and U266B1 (myeloma) cell lines.
|
1370479 |
1992 |
|
Squamous cell carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Treatment of human KB epidermoid carcinoma cells with phorbol 12-myristate 13-acetate (PMA) lead to a rapid induction of GCF RNA after 1 h and a decline to lower than control levels after 6 h. Epidermal growth factor receptor mRNAs were not increased by PMA until 2 h after treatment and were at their highest level only after GCF mRNAs were decreased.
|
1370479 |
1992 |
|
Multiple Myeloma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Elevated levels of the GCF mRNA were also noted in KATO III and AGS (gastric carcinomas), FEM-X (melanoma), and U266B1 (myeloma) cell lines.
|
1370479 |
1992 |
|
T-Cell Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The 3.0-kb GCF mRNA was found to be expressed at the highest level in HUT 102 cells (derived from a T-cell lymphoma).
|
1370479 |
1992 |
|
Gastrointestinal Carcinoid Tumor
|
0.010 |
Biomarker
|
disease |
BEFREE |
DNA content and cell cycle studies on 96 pathologically confirmed GCT specimens and anti-GCT monoclonal antibody (GCF-5 McAb) labeling study on 30 GCTs were made by flow cytometry.
|
8758338 |
1996 |
|
Dyslexia
|
0.010 |
Biomarker
|
disease |
LHGDN |
The expression of MRPL19 and C2ORF3, but not FLJ13391, were also correlated with the four dyslexia candidate genes identified so far (DYX1C1, ROBO1, DCDC2 and KIAA0319).
|
17309879 |
2007 |
|
Dyslexia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The expression of MRPL19 and C2ORF3, but not FLJ13391, were also correlated with the four dyslexia candidate genes identified so far (DYX1C1, ROBO1, DCDC2 and KIAA0319).
|
17309879 |
2007 |
|
Childhood Acute Lymphoblastic Leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Of these 1 million SNPs, six SNPs in 4 genes (HAO1 rs6140264, EPB41L2 rs9388856, rs9388857, rs1360756, C2orf3 12105972, MAN2A1 rs3776932) were strongly associated with childhood ALL risk (P(dominant)<or=0.0001 and P(trend)<0.006).
|
20189245 |
2010 |
|
Aggressive periodontitis, generalized
|
0.020 |
Biomarker
|
disease |
BEFREE |
Relationships between subgingival microbiota and GCF biomarkers in generalized aggressive periodontitis.
|
20447254 |
2010 |
|
Hippocampal atrophy
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Multiple loci influencing hippocampal degeneration identified by genome scan.
|
22745009 |
2012 |
|
Hippocampal atrophy
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Multiple loci influencing hippocampal degeneration identified by genome scan.
|
22745009 |
2012 |
|
Developmental reading disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
Lack of association between genetic polymorphisms in ROBO1, MRPL19/C2ORF3 and THEM2 with developmental dyslexia.
|
23954868 |
2013 |
|
Developmental reading disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
We aimed at discovering single nucleotide variation present in known and new candidate genes for developmental dyslexia: CYP19A1, DCDC2, DIP2A, DYX1C1, GCFC2 (also known as C2orf3), KIAA0319, MRPL19, PCNT, PRMT2, ROBO1 and S100B.
|
25877001 |
2015 |
|
Subgingival dental calculus
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
MGP concentrations in GCF of patients with subgingival dental calculus were statistically higher than those without subgingival dental calculus (p=0.032).
|
27348051 |
2016 |
|
Periodontal inflammation
|
0.020 |
Biomarker
|
disease |
BEFREE |
Clinical significance of GCF sIL-6R and calprotectin to evaluate the periodontal inflammation.
|
27810997 |
2017 |
|
Leukemia, Myelocytic, Acute
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
|
Aggressive periodontitis, generalized
|
0.020 |
Biomarker
|
disease |
BEFREE |
Periodontal parameters and GCF biomarker levels were evaluated at baseline and repeated 3 and 6 months after treatment for GAgP subjects.
|
28918557 |
2018 |
|
Subgingival plaque
|
0.010 |
Biomarker
|
disease |
BEFREE |
Four and 12 weeks after implant placement and abutment connection, a dental implant and a natural tooth were sampled in 25 patients for subgingival plaque and gingival crevicular fluid (GCF [around teeth] and peri-implant crevicular fluid [PICF] around implants).
|
29202047 |
2019 |
|
Rheumatoid Arthritis
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
At all time-points, levels of inflammatory markers in GCF were higher in RA-CP than in CP patients.
|
29589156 |
2019 |
|
Chronic Periodontitis
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
At all time-points, levels of inflammatory markers in GCF were higher in RA-CP than in CP patients.
|
29589156 |
2019 |
|
Periodontal Diseases
|
0.040 |
GeneticVariation
|
group |
BEFREE |
Data suggest that the total amount and concentration of neopterin and VCAM-1 in GCF seemed to be closely associated with periodontal disease severity in CP patients with AMI.
|
29641752 |
2018 |
|
Chronic Periodontitis
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
This study aimed to evaluate effects of periodontal treatment on GCF levels of neopterin and VCAM-1 in patients with chronic periodontitis (CP) with acute myocardial infarction (AMI) compared with systemically healthy CP patients.
|
29641752 |
2018 |
|
Periodontal inflammation
|
0.020 |
Biomarker
|
disease |
BEFREE |
There were significant positive correlations between clinical periodontal inflammation and the presence of neopterin and VCAM-1 in GCF prior to and following periodontal treatment, and between the GCF volume and clinical parameters.
|
29641752 |
2018 |
|
Acute myocardial infarction
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Data suggest that the total amount and concentration of neopterin and VCAM-1 in GCF seemed to be closely associated with periodontal disease severity in CP patients with AMI.
|
29641752 |
2018 |
|
Periodontal Diseases
|
0.040 |
Biomarker
|
group |
BEFREE |
The objective of the present study was to establish the utility of placental proteins presents in oral fluids (gingival crevicular fluid [GCF] and saliva), and periodontal disease status as early pregnancy predictors of GDM.
|
29790168 |
2018 |