MLX, MAX dimerization protein MLX, 6945

N. diseases: 40; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149793
Disease: Amaurosis Fugax
Amaurosis Fugax 		0.100 Biomarker phenotype HPO
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders 		0.100 Biomarker group HPO
CUI: C0151786
Disease: Muscle Weakness
Muscle Weakness 		0.100 Biomarker phenotype HPO
CUI: C0151811
Disease: Subcutaneous nodule
Subcutaneous nodule 		0.100 Biomarker phenotype HPO
CUI: C0231528
Disease: Myalgia
Myalgia 		0.100 Biomarker phenotype HPO
CUI: C0234428
Disease: Disturbance of consciousness
Disturbance of consciousness 		0.100 Biomarker phenotype HPO
CUI: C0856747
Disease: Aneurysm of ascending aorta
Aneurysm of ascending aorta 		0.100 Biomarker phenotype HPO
CUI: C0917798
Disease: Cerebral Ischemia
Cerebral Ischemia 		0.100 Biomarker disease HPO
CUI: C1262477
Disease: Weight decreased
Weight decreased 		0.100 Biomarker phenotype HPO
CUI: C1837388
Disease: Abnormal pattern of respiration
Abnormal pattern of respiration 		0.100 Biomarker phenotype HPO
CUI: C1962966
Disease: Retinopathy, CTCAE
Retinopathy, CTCAE 		0.100 Biomarker phenotype HPO
CUI: C2973725
Disease: Pulmonary arterial hypertension
Pulmonary arterial hypertension 		0.100 Biomarker disease HPO
CUI: C3152231
Disease: Gastrointestinal infarctions
Gastrointestinal infarctions 		0.100 Biomarker phenotype HPO
CUI: C3164445
Disease: Abnormality of aortic valve
Abnormality of aortic valve 		0.100 Biomarker disease HPO
CUI: C3203102
Disease: Idiopathic pulmonary arterial hypertension
Idiopathic pulmonary arterial hypertension 		0.100 Biomarker disease HPO
CUI: C4020969
Disease: Inflammatory abnormality of the eye
Inflammatory abnormality of the eye 		0.100 Biomarker disease HPO
CUI: C4021662
Disease: Abnormal endocardium morphology
Abnormal endocardium morphology 		0.100 Biomarker phenotype HPO
CUI: C0003504
Disease: Aortic Valve Insufficiency
Aortic Valve Insufficiency 		0.010 GeneticVariation disease BEFREE We show that rs665268 significantly correlated with the severity of TAK, including the number of arterial lesions and morbidity of aortic regurgitation; the latter may be attributed to the fact that MLX mRNA expression was mostly detected in the aortic valve. 30354298 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.010 AlteredExpression phenotype BEFREE Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis. 24857747 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.010 GeneticVariation disease BEFREE From the 21 studied single nucleotide polymorphisms (SNPs) of seven candidate genes: MLXIPL, MLXIP, MLX, ADIPOR1, VDR, SREBF1 and NR1H3, only one tag SNP rs4758685 (T→C) was found to be statistically associated with CHD (P-value = 0.02, Odds ratio (OR) of 0.83). 23840567 2013