TCN1, transcobalamin 1, 6947

N. diseases: 52; N. variants: 4
Disease: NEUROTICISM ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1842981
Disease: NEUROTICISM
NEUROTICISM 		0.040 GeneticVariation disease BEFREE In particular, high serum TSH was strongly associated with higher Persistence and Self-Directedness, and negatively correlated with Harm Avoidance on the TCI-140 and Neuroticism on the NEO-FFI, thus representing a more adaptive personality profile. 29102897 2018
CUI: C1842981
Disease: NEUROTICISM
NEUROTICISM 		0.040 Biomarker disease BEFREE Studies that used the TCI to assess Harm Avoidance or the EPQ to assess Neuroticism have found no association with the 5-HTTLPR. 19199283 2009
CUI: C1842981
Disease: NEUROTICISM
NEUROTICISM 		0.040 Biomarker disease BEFREE Contrasts between the S/S and L/L groups were significant for TCI/TPQ harm avoidance studies (P=0.0024) but not NEO neuroticism (P=0.9757). 15599377 2005
CUI: C1842981
Disease: NEUROTICISM
NEUROTICISM 		0.040 Biomarker disease BEFREE When the analysis was stratified by inventory type, there was a significant association between 5-HTTLPR and NEO neuroticism (P = 0.000016), a non-significant association between 5-HTTLPR and TCI/TPQ harm avoidance (P = 0.166), and no association between 5-HTTLPR and other anxiety-related personality traits (P = 0.944). 15108187 2004