TERF2, telomeric repeat binding factor 2, 7014

N. diseases: 125; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.030 Biomarker group BEFREE More case-to-case variability of TRF2 immunostaining intensity was noted amongst the invasive carcinomas than the other disease groups. 20625812 2011
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.030 AlteredExpression group BEFREE These results suggest that gastric carcinomas with high TRF1 and TRF2 expression may need a large quantity of the MRE11 complex. 12007281 2001
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.030 AlteredExpression group BEFREE On the other hand, carcinomas with short telomere length (shorter than 2 Kbp) expressed significantly stronger telomerase activities and higher TRF1 expression (p<0.05) and tended to express TRF2 and TIN2 at higher levels than those with long telomere length. 11494028 2001