TFAM, transcription factor A, mitochondrial, 7019

N. diseases: 147; N. variants: 4
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.020 Biomarker group BEFREE The mitochondrial transcription factor A (TFAM), plays a vital role in mitochondrial DNA (mtDNA) metabolism and has been suggested to influence IFN-β production in response to viral infection. 31495880 2020
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.020 AlteredExpression group BEFREE Interestingly, the virus infection at the late stage (at 16 h after infection) stimulated TFAM expression but decreased the levels of both NRF1 and NRF2, indicating that virus infection activated TFAM signaling independent of either NRF1 or NRF2. 31011285 2019