TFAP2A, transcription factor AP-2 alpha, 7020

N. diseases: 250; N. variants: 20
Disease: Cutaneous Melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.020 AlteredExpression disease BEFREE The loss of AP-2alpha and increased activity of cAMP-responsive element binding (CREB) protein are two hallmarks of malignant progression of cutaneous melanoma. 20805990 2010
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.020 Biomarker disease BEFREE Failure in post-transcriptional processing is a possible inactivation mechanism of AP-2alpha in cutaneous melanoma. 10864211 2000