TH, tyrosine hydroxylase, 7054

N. diseases: 321; N. variants: 71
Disease: Mechanical Allodynia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.010 Biomarker phenotype BEFREE We further found that TASK-3-containing channels anatomically define a unique population of small-sized, transient receptor potential cation channel subfamily M member 8 (TRPM8)-, transient receptor potential cation channel subfamily V member 1 (TRPV1)-, or tyrosine hydroxylase (TH)-positive nociceptive sensory neurons and functionally regulate their membrane excitability, supporting CHET3 analgesic effects in thermal hyperalgesia and mechanical allodynia under chronic pain. 31748231 2019