NKX2-1, NK2 homeobox 1, 7080

N. diseases: 319; N. variants: 20
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.130 Biomarker disease BEFREE Decreased expression of airway epithelial-specific transcription factor NK2 homeobox 1 (NKX2-1) was associated with allergic inflammation in asthma patients. 28318118 2017
CUI: C0004096
Disease: Asthma
Asthma 		0.130 GeneticVariation disease BEFREE In contrast to previous reports, our data suggest that missense mutations in the homeodomain of NKX2-1 not necessarily modify its DNA binding capacity and that this specific type of mutations may be associated with mild pulmonary phenotypes such as asthma. 24714694 2014
CUI: C0004096
Disease: Asthma
Asthma 		0.130 Biomarker disease BEFREE NKX2-1 was suppressed in airway epithelial cells from patients with asthma. 21562130 2011
CUI: C0004096
Disease: Asthma
Asthma 		0.130 Biomarker disease HPO