TLR2, toll like receptor 2, 7097

N. diseases: 749; N. variants: 15
Disease: Bacterial Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.100 Biomarker group LHGDN These studies may bring new insight for fully understanding the important role of EGFR signaling in regulating host defense and immune response by tightly controlling TLR2 induction during bacterial infections. 16115866 2005
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.100 Biomarker group LHGDN Thus, TLR2 in association with asialo-glycolipids presented within the context of lipid rafts provides a broadly responsive signaling complex at the apical surfaces of airway cells to initiate the host response to potential bacterial infection. 15146246 2004
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.100 GeneticVariation group BEFREE These findings suggest that a mutation in the TLR2 gene may predispose individuals to life-threatening bacterial infections. 11035751 2000