TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: BCG infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0860040
Disease: BCG infection
BCG infection 		0.020 AlteredExpression disease BEFREE MDSCs that were generated from murine bone marrow (MDSCs) of wild-type (WT) or <i>Cav1</i><sup>-/-</sup> mice upregulated Cav-1, TLR4 and TLR2 expression after BCG infection on the cell surface. 31849990 2019
CUI: C0860040
Disease: BCG infection
BCG infection 		0.020 AlteredExpression disease BEFREE Our results suggest that miR-21 can negatively modulate the TLR4/MyD88 signaling pathway, resulting in decreased cell viability, increased cell apoptosis and increased levels of inflammatory factors following BCG infection in macrophages. 28494464 2017