CLDN5, claudin 5, 7122

N. diseases: 104; N. variants: 2
Disease: Cerebral Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.020 Biomarker disease BEFREE These results demonstrate that absence of MCPIP1 exacerbates cerebral I/R-induced BBB disruption by enhancing the expression of MMP-9/3 and the degradation of claudin-5 and ZO-1, providing novel insights into the mechanisms underlying BBB breakdown after cerebral ischemia/reperfusion. 31261992 2019
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.020 AlteredExpression disease BEFREE DBT down-regulated the expression of MMP-9 and up-regulated the expression of claudin-5 in brain tissues of mice with cerebral infarction. 29687870 2018