TP73, tumor protein p73, 7161

N. diseases: 300; N. variants: 19
Disease: Hodgkin Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.040 GeneticVariation disease BEFREE In contrast, hypermethylation and subsequent inactivation of the P73 gene are the most common findings in malignant lymphoproliferative disorders, especially acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphomas. 16541141 2006
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.040 GeneticVariation disease BEFREE The p73 locus is commonly deleted in non-Hodgkin's lymphomas. 15475076 2004
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.040 AlteredExpression disease BEFREE Abnormal expression of p53-related protein may not play a major role in HL, because it is present in H-RS cells in only a minority of cases. 12966346 2003
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.040 PosttranslationalModification disease BEFREE Frequent inactivation of the p73 gene by abnormal methylation or LOH in non-Hodgkin's lymphomas. 12353228 2002