TP73, tumor protein p73, 7161

N. diseases: 300; N. variants: 19
Disease: Nephroblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.040 AlteredExpression disease BEFREE The high expression of p73 in the peripheral blood of children with WT was positively correlated with the clinical stage of the tumor, and was closely related with the low survival rate of patients. 31186762 2019
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.040 Biomarker disease BEFREE Preoperative venous blood p73 level serves as an underlying biomarker for the early diagnosis of WT. p73 overexpression and concomitantly decreased promoter methylation are significantly associated with poor survival in children with WT. 26184366 2016
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.040 Biomarker disease BEFREE The rest changed greatly in the methylation pattern in colorectal cancer (CRC): cyclin A1 (cyclin a1) (100%, 65/65), caudal type homeobox transcription factor 1 (CDX1) (100%, 65/65), RAR- (85%, 55/65), myogenic factor 3 (MYOD1) (69%, 45/65), cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (p15(INK4b)) (68%, 44/65), prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (COX2) (72%, 47/65), cadherin 13, H-cadherin (heart) (CDH13) (65%, 42/65), CAAX box 1 (CXX1) (58%, 38/65), tumor protein p73 (p73) (63%, 41/65) and Wilms tumor 1 (WT1) (58%, 38/65). 15526363 2004
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.040 AlteredExpression disease BEFREE Biallelic expression of p73 was also observed in paired samples of ovary cancer and Wilms' tumor. 10760569 2000