TP73, tumor protein p73, 7161

N. diseases: 300; N. variants: 19
Disease: Thyroid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.060 PosttranslationalModification disease BEFREE We found new characteristic of thyroid tumours: methylation of TP73, WIF1 and PDLIM4 TSGs, which can contribute to thyroid neoplasia. 31006665 2019
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.060 AlteredExpression disease BEFREE In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription. 21290209 2011
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.060 AlteredExpression disease LHGDN Indeed, depletion of p73 by small interfering RNA in thyroid cancer cells resulted in a reduced transcriptional activity of p53. 18234963 2008
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.060 Biomarker disease BEFREE This study was aimed to determine p73 status in thyroid tumours. 16290057 2006
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.060 Biomarker disease BEFREE Inactivation of p53 and p73 is known to promote thyroid cancer progression. 16322335 2005
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.060 Biomarker disease BEFREE Our findings suggest that the functional impairment of p73 could be involved in the development of thyroid malignancies, defining p73 as a potential therapeutic target for thyroid cancer. 14522906 2003