TPH1, tryptophan hydroxylase 1, 7166

N. diseases: 127; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.030 Biomarker group BEFREE To our knowledge, this is the first study to report an association of the 3' end of TPH1 with continuous measures of depression and anxiety. 15729745 2005
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.030 GeneticVariation group BEFREE Five single nucleoside polymorphisms of the TPH1 gene were studied in a population-based sample of postpartum Taiwanese women consisting of 120 subjects with depression or/and anxiety and 86 matched normal controls. 15544576 2004
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.030 GeneticVariation group BEFREE Polymorphisms in the regulatory region of the serotonin transporter (5-HTT), in intron 7 of the tryptophan hydroxylase (TPH) gene and in the MAOA gene were previously reported to be associated with mood and anxiety disorders, impulsivity and aggression. 11204346 2000