TPI1, triosephosphate isomerase 1, 7167

N. diseases: 184; N. variants: 10
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.090 Biomarker disease BEFREE The TIM gene family was discovered seven years ago by positional cloning in a mouse model of asthma and allergy. 18727494 2008
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. 11725301 2001
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE T cell immunoglobulin domain and mucin domain (Tim) genes are located in chromosome 5q31-33, a region repeatedly linked to asthma or asthma-related phenotypes in several populations. 19494522 2009
CUI: C0004096
Disease: Asthma
Asthma 		0.090 Biomarker disease BEFREE TPI ASM8 attenuates the allergen-induced increase in target gene mRNA and airway responses in subjects with mild asthma. 18244953 2008
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE The T-cell immunoglobulin and mucin domain (Tim) gene family in asthma, allergy, and autoimmunity. 23406933 2013
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE TIM-1, a member of T-cell immunoglobulin domain and mucin domain (TIM) gene family, was implicated as an asthma susceptibility gene in previous studies. 17117951 2006
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE TIM-1, a member of the T cell immunoglobulin and mucin domain (TIM) gene family was implicated as an asthma susceptibility gene in previous studies. 17570927 2007
CUI: C0004096
Disease: Asthma
Asthma 		0.090 Biomarker disease BEFREE A previous study suggested that TPI ASM8 had broader effects than just inhibition of eosinophils in asthmatics. 21605124 2011
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE Genomic association of the TIM family and polymorphisms in both Tim-1 and Tim-3 in different immune-mediated diseases suggest that the family may have an important role in regulating immunity, both in terms of normal immune responses and in diseases like autoimmunity and asthma. 16938542 2006