TPI1, triosephosphate isomerase 1, 7167

N. diseases: 184; N. variants: 10
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE The T-cell immunoglobulin and mucin domain (Tim) gene family in asthma, allergy, and autoimmunity. 23406933 2013
CUI: C0004096
Disease: Asthma
Asthma 		0.090 Biomarker disease BEFREE A previous study suggested that TPI ASM8 had broader effects than just inhibition of eosinophils in asthmatics. 21605124 2011
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE T cell immunoglobulin domain and mucin domain (Tim) genes are located in chromosome 5q31-33, a region repeatedly linked to asthma or asthma-related phenotypes in several populations. 19494522 2009
CUI: C0004096
Disease: Asthma
Asthma 		0.090 Biomarker disease BEFREE The TIM gene family was discovered seven years ago by positional cloning in a mouse model of asthma and allergy. 18727494 2008
CUI: C0004096
Disease: Asthma
Asthma 		0.090 Biomarker disease BEFREE TPI ASM8 attenuates the allergen-induced increase in target gene mRNA and airway responses in subjects with mild asthma. 18244953 2008
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE TIM-1, a member of the T cell immunoglobulin and mucin domain (TIM) gene family was implicated as an asthma susceptibility gene in previous studies. 17570927 2007
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE TIM-1, a member of T-cell immunoglobulin domain and mucin domain (TIM) gene family, was implicated as an asthma susceptibility gene in previous studies. 17117951 2006
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE Genomic association of the TIM family and polymorphisms in both Tim-1 and Tim-3 in different immune-mediated diseases suggest that the family may have an important role in regulating immunity, both in terms of normal immune responses and in diseases like autoimmunity and asthma. 16938542 2006
CUI: C0004096
Disease: Asthma
Asthma 		0.090 GeneticVariation disease BEFREE Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. 11725301 2001